Desmosomes are highly specialized anchoring junctions that link intermediate filaments to sites of intercellular
adhesion, thus facilitating the formation of a supracellular scaffolding that distributes mechanical forces
throughout a tissue. These junctions are thus particularly important for maintaining the integrity of tissues that
endure physical stress, such as the epidermis and myocardium.
For review, see http://www.nature.com/jid/journal/v...