[Biologie de la peau]

Table of contents The cutaneous autonomic nervous system The cutaneous sensory nervous system Bibliography The nervous system is organised in central nervous system and peripheral nervous system. The central nervous system includes the brain, spinal cord and (...)

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Hypodermis

Friday 7 May 2010 by Michel Démarchez

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Michel Démarchez CV

Friday 7 May 2010 by Michel Démarchez

Michel Démarchez has worked for more than 30 years in Research in Skin Biology, Dermatology and Cosmetics. He worked for 23 years at Galderma, a leader in Dermatology that he joins as junior searcher to eventually become Director of the Research department. In parallel, he was also consultant on skin biology at Nestlé Research Center. Skin was the biological model that he constantly used for his research. His main expertises are in embryology, wound healing and skin reconstruction, immunodermatology and pharmacology.

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Langerhans cell

Tuesday 26 January 2010 by Michel Démarchez

Langerhans cells which represent 3-6% of all cells in the epidermis, are mobile, dendritic, antigen presenting cells with a stellate appearance which reside in the suprabasal layers of the epidermis wedged in between, and in close contact with keratinocytes. Langerhans cells are derived from a mobile pool of bone marrow -derived precursors and constitute, in normal epidermis, a stable self-reproducing cell population throughout life under steady-state conditions. LCs are antigen presenting cells that may play a role either in triggering cutaneous immune activation or in sustaining cutaneous immunological tolerance depending of the environmental context.

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